Dr. Hiemstra has been providing ketamine for the treatment of depression for over 40 years. In that time, he has seen thousands of patients who have been severely depressed and not one of them has changed significantly while they were under his care. In his three years of administering ketamine for this scourge of scourges, he has seen extremes of changes in the disease, and extremes of numbers of patients who have rejoiced in those numbers.